Brimstone - Missile explosions shoot ten blood lasers in all directions.
Butt Bombs - Missile explosions will cloud up the screen, briefly confusing and dealing 10 damage to all enemies in the room.
Fire Mind - Missile explosions leave behind a fire that damage enemies on contact. Fire Mind's burn effect is overriden.
Hot Bombs - Missile explosions leave behind a fire that damage enemies on contact. Fire Mind's burn effect is overriden.
Glitter Bombs - Missile explosions have a small chance of spawning pickups.
Host Hat - Isaac becomes immune to his own airstrikes.
Pyromaniac - Isaac becomes immune to his own airstrikes.
Ipecac - Missiles have a poison effect, have a larger blast radius and deal drastically increased damage, as the +40 damage from Ipecac is run through the damage multiplier of Epic Fetus.
Mom's Knife - Missile explosions shoot a ring of ten knives.
Monstro's Lung - 2 to 4 additional crosshairs orbit the main crosshair, and missiles are fired onto each crosshair.
Mysterious Liquid - Every missile explosion leaves a small, lasting pool of creep.
The pool of creep left by the explosion is larger.
Polyphemus - Increased tear delay, but massively increases the missiles' blast radius and damage, as Polyphemus' damage multiplier is run through the damage multiplier of Epic Fetus.
Sad Bombs - Missile explosions fire ten tears in all directions. The shrapnel's damage is not run through the damage multiplier of Epic Fetus.