Giant Cell

Causes Isaac to spawn micro-Isaacs when he takes damage, which chase and shoot at nearby enemies.

Quote

"Micro friends"

Effects

• Whenever Isaac takes damage, he summons a Minisaac familiar that chases nearby enemies and shoots at them from the cardinal directions.
• • Minisaacs deal 1.35 damage per tear and have a tear delay of 8.
  • Minisaacs persist between rooms and floors.
  • The familiars can die from getting hit by enemies and enemy projectiles.
  • The familiar cap for Giant Cell is 16, after which taking damage will not spawn a new Minisaac.
  • Summons colored Minisaacs dependent on character.
  • The familiars have the same attack style as your chosen character; Azazel Minisaacs will fire Brimstone, and The Forgotten Minisaacs will use the bone club.
  • • This does not apply for Tainted Azazel; his familiars will fire regular tears.
    • When playing as The Forgotten, the familiars take the style as either The Soul or The Forgotten, depending on who gets hit.
  • Sacrificial Altar converts all Mini-isaacs into 1 Penny each upon use.
  • BFFS! increases damage dealt by Minisaacs by 40%
  • Baby-Bender does not cause their shots to home.
  • Box of Friends has no effect.

Found in

• Treasure Room
• Treasure Room (Greed Mode)