BFFS!

Increases the size and effectiveness of most familiars.

Quote

"Your Friends Rule!"

Effects

• Visually increases the size of all familiars by 25%, and improves the effectiveness of most of them.
• • Doubles the damage of Familiars that deal damage through tears and contact damage.
  • • Only affects familiars that deal a set amount of damage. Has no effect on most familiars that scale with Isaac's damage.
    • Has no effect on Creep generated by familiars.
  • For pickup-generating familiars, increases the frequency that they drop pickups.
  • • Familiars that require clearing a certain number of rooms will require one less room.
    • Familiars that have a random chance to drop items have a higher chance.
    • Familiars that pick up consumables require less, except Dark Bum which is unaffected.
  • Some familiars have unique synergies.

Synergies

• BBF - Doubles impact damage and increases explosive damage by 25.
• Bob's Brain - Doubles impact damage and increases explosive damage by 25.
• Blood Oath - Adds 2 full hearts' worth of bonuses if any health is drained at all, e.g. losing 1 heart gives the bonuses of 3 hearts.
• Incubus - Deals double Isaac's damage instead of copying it.
• Fate's Reward - Deals double Isaac's damage instead of copying it.
• Holy Water - Double water damage, spawn a blue flame at point of impact.
• Juicy Sack - Spawns an extra Blue Spider.
• Lil Spewer - Increases the creep pool's size, but not its damage.
• Mystery Egg - Spawns a champion variant of the enemy, even if the enemy can't normally be a champion.
• Lost Soul - Gives the Lost Soul a Holy Mantle effect.

Found in

• Shop
• Shop (Greed Mode)