The Binding of Isaac Wiki

Rune Bag

Rune Bag

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Spawns a familiar that drops a random rune every 5-6 rooms.

Quote

"Rune generator"

Effects

  • Spawns a familiar that drops a random rune alternatingly every 5 or 6 rooms.
    • If there are no runes unlocked, it will drop cards instead.

Synergies

Found in

  • Golden Chest
  • Secret Room
  • Treasure Room
  • Treasure Room (Greed Mode)
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