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Gives Isaac the chance to fire spore tears that stick to enemies and blow up after a few seconds, dealing damage and poisoning nearby enemies and releasing more spores.


"Spore shot"


  • Gives Isaac the chance to shoot a spore that, in addition to dealing damage, will stick to enemies.
  • Spores will explode 2.5 seconds after sticking to an enemy, dealing 5 damage to and poisoning nearby enemies and firing four more spores in a cross pattern.
    • Spores produced from Isaac's spores have homing.


  • Lost Contact
    - Stuck tears will block projectiles shot by attached enemies, crippling or even stopping their ability to shoot projectiles entirely.
  • Mom's Knife
    - No effect.

Found in

  • Treasure Room
  • Treasure Room (Greed Mode)


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