Tooth and Nail

Isaac periodically turns into a spiked statue, briefly becoming invulnerable and dealing contact damage.

Quote

"You feel prickly"

Effects

• Every 6 seconds, Isaac turns to stone and sprouts spikes for 1 second. While Isaac is in this state, he is immune to damage and deals 40 contact damage.
• • Isaac flashes white four times before turning to stone on the fourth flash. First three flashes are accompanied by a "ticking" sound, the final one with the spike extension sound of a mimic chest.
  • Unlike Gnawed Leaf, Isaac can still move and shoot tears.

Found in

• Treasure Room
• Treasure Room (Greed Mode)