The Binding of Isaac Wiki

Serpent's Kiss

Serpent's Kiss



Tears have a chance to apply a poison effect to enemies. Isaac poisons enemies on contact. Poisoned enemies have a chance to drop a black heart when killed.


"The kiss of death"


  • Grants a chance to fire poison tears, each tick dealing damage equal to Isaac's.
    • Poison from the shots will tick 2 times.
  • Inflicts poison on enemies who make contact with Isaac.
    • Contact poison will tick 6 times.
  • Enemies who are killed by contact poison have a 20% chance to drop black hearts.

Found in

  • Treasure Room
  • Treasure Room (Greed Mode)


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