The Binding of Isaac Wiki

Guppy's Tail

Guppy's Tail


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Room clear awards have a 1/3 chance of being replaced with a chest and a 1/3 chance being replaced with nothing.




  • Grants a 1/3 chance of replacing a room clear award with a normal chest or a locked chest, but also a 1/3 chance to replace it with nothing at all.
    • The effect does not apply to coins dropped in in Greed Mode.
  • This item belongs to the Guppy set. Collecting three items from this set will transform Isaac into Guppy.


  • The Left Hand
    - Turns all chests into Red Chests, allowing you to get Red Chest items much more quickly (including Guppy items).
  • Mom's Key
    - Increases the number of drops from chests and counteracts the increased chance to run into Locked Chests.

Found in

  • Curse Room
  • Devil Room
  • Red Chest
  • Curse Room (Greed Mode)
  • Devil Room (Greed Mode)


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