Tier
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Grants two Black Hearts. While Isaac has no red hearts, grants flight and periodically grants an invincibility shield for a few seconds.
Quote
"I reward an empty vessel"
Effects
- Grants 2 Black Hearts on pickup.
- When Isaac has no Red Hearts:
- Grants flight.
- A 10-second shield activates when Isaac is in a room with enemies and the seconds on the timer hit 00, 20 or 40 at least twice.
Synergies
- Brittle Bones - The empty bone hearts will trigger Empty Vessel.
Found in
- Devil Beggar
- Devil Room
- Devil Room (Greed Mode)