When Isaac uses a card, pill, or rune, he also uses a copy of every card/pill/rune he used after picking up Echo Chamber.
"I can see see the future future future"
- When using a pill or card, Echo Chamber activates one of every pill type and card type that has been previously used since obtaining Echo Chamber.
- Regardless of how many times a single type of card, pill, or rune has been used previously, it will only activate the effect once.
- Rune of Jera - Allows for infinite duplication of items and consumables, because Jera's effect will activate when using any consumable.
- Secret Room
- Shop (Greed Mode)