Cone Head

Grants a Soul Heart. Gives Isaac a chance to ignore any damage taken.

"Hard headed!"

• Grants +1 Soul Heart.
• Any damage dealt to Isaac has a 20% chance to be ignored.
  • These include damage through tears, contact, explosions, cursed doors, Blood Donation Machines, and Demon Beggars.
  • Contact damage with enemies is difficult to avoid as the damage negation does not provide invincibility frames.
  • Isaac flashes briefly blue when damage is negated. The flash can occur even while invincible from taking a hit or using an invincibility effect.

• 
  Razor Blade - Has a chance to block the damage inflicted by Razor Blade, but the damage up from it still applies, allowing you to stack more damage than usual.

• Treasure Room
• Treasure Room (Greed Mode)